Lausanne, Vaud, Switzerland
Over the past 9 years, I’ve worked in different international laboratories in Europe, exploring stem cell biology in its many forms, driven by my curiosity for genome editing, development and disease modelling. I recently completed my PhD in Bioengineering at EPFL, where I built the lab’s intestinal organoid platform from scratch to then develop an end-to-end experimental workflow to culture intestinal organoids and investigate their circadian rhythms in real time, by integrating an organ-on-chip system with live microscopy. This PhD work was recognized with two Best Poster awards and a short-talk selection. My current interests lie at the interface of business development, R&D and New Approach Methodologies (NAMs), with a focus on building more predictive, robust and human-relevant research models.
Naef Lab - Laboratory of Computational and System Biology
"Characterizing the role of geneX during ageing, using intestinal organoids derived from mice". Skills: intestinal organoid generation and culture, immunostaining, confocal microscopy, CRISPR-Cas9 technology, qPCR, western blot, nuclear extraction.
"Methylome and transcriptome analysis of human-derived fibroblasts with MeDeCom".
"Identification and validation of differentially expressed genes from transcriptomic data, from small intestinal organoids of young and aged mice"
"Morphometrics of RRP5 mutants in Arabidopsis thaliana". Skills: A. thaliana crossings, cloning, microscopy, supervised data collection and analysis with Ilastik segmentation tool and KNIME platform.
"Investigation into the role of CYFIP1 in neurogenesis - Construction of a multiplex CRISPR/Cas9 single lentiviral plasmid" "Differentiation and validation of a dual-reporter hPSC line" Skills: human embryonic stem cells culture (hESC), cloning, CRISPR-Cas9 technology, flow cytometry, confocal microscopy, Karyotyping analysis.