Israel
I am the Director of the Heart Failure Institute at Sheba Medical Center and a Full Professor of Cardiology at Tel Aviv University. My research spans both clinical and basic science, with a focus on two key areas: Clinical Research and Innovation: As an interventional and structural cardiologist, I focus on heart failure and valvular heart disease. A significant part of my work revolves around the SHEBAHEART big data registry, which contains data from hundreds of thousands of patients. This registry has contributed to numerous publications in preventive cardiology, heart failure, and echocardiography. Currently, my primary clinical focus is on tricuspid valve interventions. Additionally, our registry serves as the foundation for an AI-augmented POCUS project (AISAP), now FDA-approved and integrated into clinical practice at Sheba. Basic Science and Translational Research: I hold a PhD in Biophysics from the University of California, Berkeley, where I was among the first to explore the biophysical mechanisms of irreversible electroporation (IRE). Over the past two decades, I’ve remained active in this field as it evolved into pulsed field ablation (PFA) — now an established clinical technology. My lab continues to investigate PFA, with a focus on optimizing ablation protocols and understanding how electroporation induces cell death without thermal injury. This work has led to multiple publications, bridging basic science with clinical innovation.
Research in the field of Vascular Biology and Irreversible Electroporation