Durham, North Carolina, United States
Dr. Saban is an immunologist and leukocyte biologist with a strong background in eye health and disease. He has extensively studied various areas of the visual system to this end, including the retina, anterior chamber, and ocular surface. These sites have served as robust models in elucidating networks that underpin immune cell function in the tissue context. The Saban lab is currently focused on immune cell crosstalk with tissue cells, namely fibroblasts, nerves, and epithelial cells. His lab is establishing an immunomics approach to address questions through computational tools, deep profiling flow cytometry, intravital imaging, and cre-lox technologies. Diseases of study include chronic eye allergy, meibomian gland dysfunction, and conjunctival fibrosis. The lab is also developing tools to study the role of microglia in retinal degeneration.
Ophthalmology and Immunology
Ophthalmology and Immunology
Ophthalmology and Immunology
Antigen Presenting Cells in Corneal Immunity
Immunobiology of the cornea
Immune Privilege of the Eye
Gene therapy and immune regulation relevant to conditions of the retina