London, England, United Kingdom
Dr Michael Grant MB BCh BAO BSc(Hons) MSc PGCert DPM FHEA MFPM MRCP(UK) I completed my medical degree at Queens University, alongside a 1st class Bachelor of Science in Molecular Oncology at the University of Leeds. During these I accrued almost 2 years of varied lab benchwork experience through competitive, funded studentships that resulted in several primary research presentations and publications. I secured my first choice position in the highly competitive NHS Academic Foundation Programme (AFP) in London, working in Medical Oncology at Barts Health NHS Trust. The focus of this was translational oncology at Barts Cancer Institute, under the supervision of Professor Thomas Powles (“Nature’s 10”, 2023). I served as investigator on commercial and investigator-led trials, and worked on a range of academic projects in immuno-oncology. I continued this work in a clinical research fellowship with Prof Powles, conducting translational research and clinical development across a range of trials in different cancer indications - alongside obtaining a PGCert in teaching and an honorary appointment as a lecturer in oncology. Towards the end of my fellowship, I was headhunted for a clinical development director role in a Francis Crick Institute/CRUK biotech developing first-in-human, advanced therapeutics for solid tumours. Since transitioning to industry, I have gained extensive clinical development experience across a range of therapeutic agents (including compounds that have gained ‘Breakthrough Therapy’ and ‘Innovative Licensing and Access Pathway’ designations), with a particular focus on immuno-oncology therapies. Undertaking medical director roles in biotech - occasionally as the only in-house physician - has cultivated a broad and adaptive skillset, building on my experiences as a clinician scientist. Having been responsible for leading international trials in solid and haematological cancers (Phase I to III), I have experience in end-to-end trial design, key study documentation production, successful regulatory submissions/responses, statistical and translational analysis, pharmacovigilance, clinical strategy, and medical monitoring for pivotal & registrational studies. Whilst working in industry, I have continued to hold academic positions and practice clinically in NHS medical oncology services in London. I have completed my Royal College of Physicians' membership examinations in internal medicine (MRCP) and pharmaceutical medicine (DPM), and hold a Masters in Experimental Therapeutics from the University of Oxford's Department of Oncology.
Senior Clinical Research Fellow in Medical Oncology at St Bartholomew's Hospital, Barts Health NHS Trust
Honorary Clinical Lectureship at the Barts Cancer Institute, Queen Mary University of London.
Supporting the clinical and academic work being undertaken by the Barts Cancer Institute via the cancer clinical trials team at St Bartholomew's hospital.