Germany
I am an experienced and ambitious scientist with over 10 years of expertise in oncology, hematology, and immunology. My academic training, including my PhD and postdoctoral research, focused on the genetic and epigenetic changes in the progression of myelodysplastic syndromes to acute myeloid leukemia, as well as the phenotypic characterization of lymphocyte subpopulations. I subsequently advanced my career as a scientist and group leader at Immatics, focusing on developing innovative, personalized T cell immunotherapies to improve outcomes for cancer patients worldwide. I am now eager to explore new directions, broaden my expertise across additional fields, and contribute to a dynamic and creative team.
Development of targeted T cell immunotherapies for cancer patients - group leader since January 2024 - coordination of preclinical projects until final data package (initial efficacy and safety) - supervision of technicians - planning of lab activities of several projects including people management - time line management - data evaluation, presentation and trouble shooting - interdepartmental work - database maintenance
Development of targeted T cell immunotherapies for cancer patients - TCR identification and re-expression - co-culture assays, ELISA, flow cytometry - data evaluation, presentation, trouble shooting - method development - database maintenance
Routine diagnostics of sample material of internal and emergency patients. - analyses of blood, urine, cerebrospinal fluid, puncture fluid - blood typing, serological compatibility tests - hardware maintenance and calibration - interaction with medical staff
At the Department of Hematology, Oncology and Stem-Cell Transplantation of the University Hospital Freiburg. I was working on the phenotypic and genetic characterization of lymphocyte subpopulations in acute myeloid leukemia. Main techniques applied: - multicolor fluorescence-activated cell sorting (FACS) - fragment analysis - next-generation sequencing (NGS)
At the Department of Hematology, Oncology and Stem-Cell Transplantation at the University hospital Freiburg. I focused on genetic and epigenetic changes in the progression of myelodysplastic syndromes to acute myeloid leukemia including single-cell analyses to reveal clonal evolution. Attendance of national and international meetings: - poster presentation at the European Hematology Association (EHA) in Madrid 2017 - talk at the German, Austrian and Swiss Societies for Hematology and Medical Oncology (DGHO) in Stuttgart 2017 Data presentation within seminars and workshops of the Department of Hematology, Oncology and Stem-Cell Transplantation at the University hospital Freiburg and at the Research Day of the University Hospital Freiburg. Techniques used during my PhD: - design of a custom gene panel for NGS including library preparation, sequencing and data analysis - validation of mutations found by NGS by orthogonal methods (Sanger sequencing, pyrosequencing) - methylation analysis (450K array) and RNA expression analysis (qPCR) - single-cell analysis by NGS and Sanger sequencing - writing an application for mice experiments - mice experiments included cloning, lentivirus production, infection of murine bone marrow, retrobulbar transplantation as well as blood and bone marrow analysis by FACS
24-hour care of young adults with autism