Dennis Heller

Sr. Director, Early Drug Development Services, Certara Drug Development Solutions

Canada

About

Accomplished and passionate executive with a proven track record with 25+ years providing operational management, scientific leadership, consulting, and technical sales to the pharmaceutical and biotech industries. Technical knowledge across the ADME discipline, with particular depth in radiolabel studies from in vitro, non-clinical to clinical hAME studies and dosimetry. Knowledge of regulatory requirements for IND and NDA-enabling DMPK programs including bioanalysis, metabolites in safety testing, drug-interaction, and radioprofiling/excretion/mass balance studies. Creative leader effective in achieving critical business objectives and meeting performance targets by leveraging strong influencing and communication skills to build win-win relationships with diverse business partners and stakeholders. Early career experience in academia in both teaching and grant funded research programs in the area of radiation biology.

Experience

  • Certara (Full-time · 5 yrs 6 mos)
    • Sr. Director, Early Drug Development Services
      Apr 2024 - Present · 2 yrs 3 mos

      Provide consultancy services to pharmaceutical and biotech companies in the areas of non-clinical and clinical DMPK/ADME studies, including; project lead to design and manage IND and NDA-enabling ADME programs for drug metabolism, PK, DDI, and radiolabel studies, vendor management, report review and preparation, gap analysis, as well as human radiolabel dosimetry estimations.

    • Director, Early Drug Development Services
      Jan 2021 - Mar 2024 · 3 yrs 3 mos

  • Principal at DP Heller Consulting LLC
    Aug 2020 - Dec 2020 · 5 mos

    Provided consulting services to pharmaceutical and biotech companies in the areas of non-clinical and clinical PK/ADME studies, including; study design, project management, vendor management, report review, gap analysis, and human radiolabel dosimetry estimations.

  • VP, Pharmaceutical Development/Deputy Site Head at WuXi AppTec/XenoBiotic Laboratories, Inc.
    Jul 2004 - Jul 2020 · 16 yrs 1 mo

    Responsible for site operations, technical consulting and business development for DMPK/ADME and bioanalytical services, as well as client management at the NJ Site of WuXi AppTec's Lab Testing Division.

  • Vice President Of Business Development at Pharmaceutical Profiles
    2000 - 2003 · 3 yrs

    Led business development efforts in North America; evaluated pharmaceutical/biotech/drug delivery company products for their need for nuclear gamma scintigraphy imaging and regional gut absorption services.

  • Associate Director, Imaging and Radiopharmaceutical Research at MDS Pharma Services (formerly Phoenix International Life Sciences)
    1996 - 2000 · 4 yrs

    Conducted human radiolabel (hAME) studies, nuclear medicine imaging studies and dosimetry, Radiation Safety Officer