Defne Şen

Undergraduate Student Researcher @ Erbay Lab | Molecular Biology, Laboratory Skills

United States

About

Currently pursuing a Bachelor of Science in Microbiology, Immunology, and Molecular Genetics at UCLA, while contributing as an undergraduate researcher at Erbay Lab. Research centers on elucidating the role of FMRP in atherosclerosis, leveraging advanced methodologies like Lysosomal Immunoprecipitation and siRNA transfection. Core competencies include molecular biology, laboratory techniques, and protocol optimization. Collaborative research at Erbay Lab emphasizes mitochondrial function and cell senescence. The role reflects a commitment to scientific discovery and precision, aligning with UCLA's values of innovation and academic excellence. Dedicated to fostering a culture of teamwork and exploration, this researcher contributes a unique perspective and technical expertise to furthering impactful studies.

Experience

  • Undergraduate Student Researcher at Erbay Lab
    Jan 2026 - Present · 6 mos

    I am conducting molecular biology research to explain the mechanisms of FMRP in an atherosclerotic context. My workflow involves rigorous protocol optimization and characterization of mouse models (WT and FMRP -/-). Key methodologies I am utilizing include: Lysosomal Immunoprecipitation (LysoIP): Isolating HA-tagged lysosomes from Bone Marrow-Derived Macrophages (BMDMs). Genetic Manipulation: Utilizing electroporation for siRNA transfection in PBMCs. Cell Biology: Investigating mitochondrial function and cell senescence pathways.

  • Camp Counselor at Geleceğin Yıldızları - Future Stars Inc.
    Jul 2022 - Present · 4 yrs

    As an ongoing camp counsellor for Geleceğin Yıldızları, I create a safe, fun, and engaging environment for children and youth. My 3-week training focused on communication skills, which helps me lead activities such as sports, arts, music, and group discussions. I am a positive role model, instilling values like teamwork and respect. I prioritize safety and have experience with emergency procedures. I build strong relationships with campers and collaborate with fellow counsellors to create diverse and engaging programming. Working with Geleceğin Yıldızları has been an enriching experience that allows me to develop skills in leadership, communication, and teamwork. I am passionate about making a difference in the lives of children and am committed to continuing my work with this organization.

  • Inclusion Specialist at Alpha Delta Pi Sorority
    Dec 2024 - Feb 2026 · 1 yr 3 mos

  • Research Assistant at DNA Barcoding of RC Plants
    Nov 2022 - Feb 2025 · 2 yrs 4 mos

    As a current research assistant for the DNA Barcoding of RC Plants Initiative, I am responsible for conducting laboratory experiments and assisting with data analysis for a thesis research project aimed at identifying and cataloging the plant species present in the Robert College campus using DNA barcoding techniques. In this role, I have gained experience in various laboratory techniques, including DNA extraction and learned about the workings of PCR amplification. I work with precision and accuracy to ensure that each experiment is conducted according to protocols and standards.

  • Robert College International Model United Nations (Full-time · 3 yrs 8 mos)
    • RCIMUN RCSA Manager
      Oct 2022 - Feb 2025 · 2 yrs 5 mos

    • RCMUN Member
      Jul 2021 - Feb 2025 · 3 yrs 8 mos