David Soler Segovia, PhD

Scientific Lab. Lead & Project Coordinator | PhD in Medicine | Translational Research Specialist | Preclinical & Clinical Data Analysis

Greater Barcelona Metropolitan Area

About

PhD in Medicine & Biotechnology specialized in bridging the gap between bench science and clinical application within a Translational Research framework. From the beginning of my academic journey, I have been deeply committed to understanding the impact of environmental health, pollution, and climate change on human pathology—a research line that has become my core area of expertise. Throughout my career at Vall d'Hebron Institute of Research (VHIR), I have led technical operations in high-impact studies, including preclinical analysis and large-scale international collaborative projects focused on the respiratory effects of the exposome. Core Competencies: 🎯 Environmental Health & Exposome: Specialized in researching the immunological and inflammatory effects of environmental pollutants (projects EXIMIOUS - H2020 and ASHES). 🎯 Translational Operations: Expert in the lifecycle management of human biospecimens, ensuring data integrity and seamless bridge-to-clinic workflows. 🎯 Preclinical Research: Proven track record in assay validation and method optimization, including specialized work with extracellular vesicles. 🎯 Strategic Collaboration: Key technical liaison in national (ASHES, FIS) and international (EXIMIOUS - H2020) consortia. 🎯 Scientific Excellence: Recognized with 5 communication awards and a strong publication record (+7 articles) in high-impact journals.

Experience

  • Vall d’Hebron Institute of Research (VHIR) - Vall d'Hebron Institut de Recerca (Barcelona, Catalonia, Spain)
    • Scientific Laboratory Lead | Postdoctoral Researcher
      Sep 2025 - Present · 10 mos

      Directing the scientific-technical operations of the Pneumolgy Translational Research laboratory. I act as the primary liaison between bench science and clinical reality, ensuring that laboratory workflows provide high-value insights for medical teams and therapeutic development. Key Highlights: 🔬 Preclinical Study Leadership: Leading the technical execution and analysis of a preclinical study, optimizing experimental design and ensuring data robustness for potential clinical transition. 🔬 Translational Operations: Managing the end-to-end lifecycle of patient-derived samples, maintaining strict protocols for biological integrity, ethics, and data traceability. 🔬 Clinical Support & Strategy: Providing specialized technical support to medical teams, translating clinical observations into actionable laboratory-based research goals. 🔬 Cross-functional Liaison: Harmonizing methodologies and data exchange between the laboratory and clinical departments to accelerate translational discovery. 🔬 Methodological Innovation: Implementing advanced laboratory standards and Standard Operating Procedures (SOPs) to enhance reproducibility and operational efficiency.

    • Clinical Scientist | PhD fellow
      Sep 2020 - Present · 5 yrs 10 mos

      Managed the technical and scientific execution of translational pneumology research projects focused on the immunological and inflammatory effects of environmental pollutants. Participating within interdisciplinary teams with focus into bridge the gap between basic science and clinical application. Key Highlights: 🔬 Strategic Project Participation: Served as a fundamental technical contributor for the H2020 EXIMIOUS international consortium and national projects such as ASHES and FIS, researching the effects of the exposome on respiratory health. 🔬 Patient-Derived Data Management: Performed in-depth analysis of environmental, clinical, and molecular data, ensuring high-quality results from patient-derived samples. 🔬 Advanced Molecular Diagnostics: Gained extensive experience in handling complex biological datasets and molecular techniques to support evidence-based medicine. 🔬Scientific Excellence: Authored +5 peer-reviewed articles in high-impact journals and was granted 5 communication awards for excellence in data presentation.

    • Junior Scientist | MSc fellow
      Jan 2020 - Sep 2020 · 9 mos

      Focused on advanced biotechnology techniques for drug delivery systems and preclinical research. Worked on the development of innovative therapies for rare diseases, specifically targeting the Blood-Brain Barrier (BBB). Key Highlights: 🔬 Preclinical Methodology: Executed the purification and characterization of extracellular vesicles (EVs) as a delivery vehicle for enzyme replacement therapy. 🔬 Method Optimization: Contributed to the setup of an optimized protocol for obtaining in vivo EVs for preclinical analysis in Fabry’s disease. 🔬Scientific Synthesis: Conducted an extensive literature review and strategic analysis on overcoming the Blood-Brain Barrier using EV-driven therapies. 🔬Adaptability & Rigor: Demonstrated high resilience by pivoting project goals due to COVID-19 restrictions, delivering a high-quality Master's thesis titled "Enzyme Replacement Therapy driven by Extracellular Vesicles".

  • BSc Trainee | Undergraduate Researcher at Universitat Politècnica de València (UPV) Departamento de Ciencia Animal
    Mar 2019 - Jul 2019 · 5 mos

    Developed a research project focused on molecular diagnostics and animal physiology within the Animal Science Department. Gained foundational experience in experimental design and high-precision laboratory techniques. Key Highlights: 🔬 Molecular Diagnostics: Hands-on experience in DNA extraction and RT-qPCR for pathogen detection and gene expression analysis. 🔬 Experimental Execution: Performed standardized protocols for animal handling and sample collection in a controlled research environment. 🔬Analytical Thinking: Evaluated the effects of different dietary habits (low fishmeal diets) on animal (sparus aurata) immune response after a parasitary infection (Diplectanum sp.). 🔬Early Career Excellence: Completed the project as part of the High Performance Academic Group (ARA), demonstrating early commitment to scientific rigor.