Bern, Berne, Switzerland
- Database Management: gathering, restructuring and visualizing process data for data trending and analysis (Python and Excel) - Change Control Owner leading cross-functional meetings to assess activities and define a strategic approach to implement changes eg equipment changes, facility adjustments or general manufacturing process optimizations - Quality Investigation Owner acting as a submitter and investigator, including root cause and CAPA definition, supervising execution of follow-up activities and performing effectiveness checks - Role as a trainer to optimize GMP on site eg creation of a GDP hands-on training and acting as a trainer for GMP Operations to improve Quality site wide - Regular GEMBA walks in manufacturing production to assess process gaps and implement process optimizations - Technical writing including WIs, SOPs and FRMs - Periodic review and updates of the Process Risk Assessment identifying potential process risks and implementing risk reduction measures
- Change Control Management for filling line optimizations - Project Work to generate lean processes - Physical assessment of filling line issues and potential filling line optimizations
Traineeship in HTS - Investigation of neuroblastoma cell phenotypes induced by chemical compounds using lab automation and multi-channel confocal microscopy. - Cell culture of mammalian cells - Lab automation (Tecan) for cell fixation and staining - 3D imaging using confocal microscopy (Harmony software)
Investigation of asymmetric cell division in murine hematopoietic stem cells using time-lapse microscopy and a computational analysis pipeine.
Research project: Engineering of a plug and play platform to produce recombinant antibodies in mammalian cells.
Research Project: Investigating the effect of protein overexpression and knockdown on the cell cycle length of heatopoietic stem cell daughters after lysosomalasymmetric cell division. Virus production, time-lapse microscopy, cloning, sequencing.
Investigating the effect of the different gene deletions on the production of sorbicillinoids in Trichoderma reesei