Chrysa Papadopoulou

Researcher Phd Candidate at University of Zurich, Cantonal Hospital St. Gallen

Switzerland

About

I am a passionate bioinformatician with experience in analyzing bulk RNA-seq, single-nuclei RNA-seq, scRNA-seq, spatial transcriptomics and single-cell immune repertoire seq datasets to decipher the interplay of Fibroblastic reticular cells (FRCs) and T cells in cancer and during lymph node organogenesis.

Experience

  • Researcher Phd Candidate at University of Zurich
    Jan 2022 - Present · 4 yrs 7 mos

    I am working in the group of Prof. Burkhard Ludewig at the Kantonsspital St. Gallen. I research computationally: 1. the identity, differentiation and functions of Fibroblastic reticular cells (FRCs) in forming critical fibroblastic niches and promoting antitumor T cell immunity in lung cancer 2. the developmental origin, location, structural differences between serially connected accessory lymph nodes and their impact on anti-viral and anti-tumor immune responses

  • ETH Zürich (1 yr 10 mos)
    • Scientific Assistant
      Jul 2021 - Dec 2021 · 6 mos

      I am working on the development and implementation of new functionality to an ocean microbial genomes web database at the Sunagawa Lab at Institute of Microbiology

    • Research Intern
      Apr 2021 - Jul 2021 · 4 mos

      Laboratory for Systems and Synthetic Immunology, D-BSSE Implementation of new functionality to "AbNetForests" R package

    • Master Thesis Project
      Sep 2020 - Mar 2021 · 7 mos

      I am performing my master thesis at Laboratory for Systems and Synthetic Immunology. "AbNetForests: an R package for B cell mutational networks from single-cell immune repertoire sequencing data" "AbNetForests" R package facilitates the study of B cell evolution and somatic hypermutation. The framework involves customizable options for clonal lineage assignment, inference, visualization of B cell mutational networks and assessment of repertoire diversity by processing single-cell immune repertoire sequencing data

  • Research Group Member at Diana Lab
    Feb 2017 - Jun 2018 · 1 yr 5 mos

    University of Thessaly, Hellenic Pasteur Institute i) Evaluation of de novo algorithms for the identification of miRNA:mRNA interactions ii)Combinatorial prediction of target microRNAs Diploma Thesis : Evaluation of microRNA target prediction algorithms with experimentally supported targets

  • Undergraduate Teaching Assistant at University of Thessaly
    Feb 2017 - Jun 2017 · 5 mos

    CE213 Numerical Analysis

  • Summer Intern at Centre for Research & Technology Hellas (CERTH)
    Jul 2016 - Aug 2016 · 2 mos

    Design, optimization and testing hardware and software components of embedded systems using FPGAs