Chris Matheson

Medicinal Chemistry Group Leader at Domainex

Cambridge, England, United Kingdom

About

An experienced medicinal chemist and drug hunter with an emphasis on leading multi-disciplinary teams and fostering close collaboration to realize project milestones on projects spanning all phases of the drug discovery pipeline, from hit-ID to candidate nomination. Often working at the interface of medicinal chemistry, computational chemistry and assay biology, I have a proven track record of driving project success across a wide range of therapeutic areas, including BRo5/degrader space and covalent drug discovery. Throughout my career I have built and managed high-performing teams of researchers, partnering closely with clients to dictate strategy, managed external CROs and delivered high-level presentations to key stakeholders. I am passionate about mentoring and developing the next generation of scientists and instilling a culture of scientific curiosity, open and honest communication and ensuring all team members are valued and fully invested in the project plan. Key skills: - Medicinal chemistry strategy and project leadership - Structure-based and data-driven drug design - Managing multi-disciplinary project teams - Working closely with DMPK specialists - Coordinating external collaborators and overseas CROs I'm always looking to connect with fellow researchers, past, present and future collaborators and leaders in the drug discovery landscape!

Experience

  • Domainex (6 yrs 1 mo)
    • Group Leader
      Jul 2024 - Present · 2 yrs

    • Team Leader
      May 2022 - Jul 2024 · 2 yrs 3 mos

    • Associate Principal Scientist
      Jun 2021 - May 2022 · 1 yr

  • University of Colorado Denver (6 yrs 11 mos)
    • Post-Doctoral Research Fellow
      Jan 2014 - Nov 2019 · 5 yrs 11 mos

    • Visiting Research Associate
      Jan 2013 - Jan 2014 · 1 yr 1 mo

  • Catalyst Development Chemist at Johnson Matthey
    Jul 2007 - Aug 2008 · 1 yr 2 mos

    Development of novel titanium based catalysts for the industrial scale production of polyethylene terephthalate (PET).