John Cassidy

Sr. Director of IT @ ParabilisMed | Strategic IT Operations

North Chelmsford, Massachusetts, United States

About

With over 20 years of experience in the IT industry, I am a seasoned leader and innovator who is passionate about managing and securing IT operations, aligning technology with strategic business goals, and optimizing budget and resources. I currently serve as the Sr. Director of Information Technology at Parabilis Medicines, a biotech company that is developing breakthrough medicines, pioneering a new class of drugs to address the limitations of today’s precision medicines and achieve universal druggability.. My expertise lies in building and nurturing highly skilled, driven, and curious teams that can deliver on complex and ambitious IT and electronic data projects. I have successfully implemented and coordinated systems, policies, and procedures that ensure the security of data, network access, and backup systems. I have also spearheaded the migration of many services to SaaS offerings or AWS, and established and managed vendor relationships that foster collaboration and innovation. I am always eager to connect with like-minded professionals and discuss how we can drive progress in the realm of technology and IT management.

Experience

  • Parabilis Medicines (Full-time · 5 yrs 11 mos)
    • Sr. Director, Information Technology
      Mar 2025 - Present · 1 yr 4 mos

      In my role as Sr. Director of IT at Parabilis Medicines, I lead the technology strategy and infrastructure that underpins our mission to accelerate the development of a new modality of peptide therapeutics. I collaborate closely with Data Science, R&D, and Clinical teams to integrate advanced analytics platforms and real-world data into decision-making. By overseeing the design and security of our IT systems, ensuring they meet GxP, HIPAA, and other regulatory requirements, I help maintain a robust and compliant environment for large-scale data processing and research. I also focus on building and guiding a high-performing IT team, fostering a culture of innovation where collaboration and continuous learning drive results. From evaluating and negotiating vendor partnerships to implementing machine learning projects, my goal is to deliver scalable solutions that enhance Parabilis’ data-driven approach to drug discovery. Through this work, I aim to contribute meaningful advancements to global health while supporting an agile, forward-thinking organization.

    • Director, Information Technology
      Aug 2020 - Mar 2025 · 4 yrs 8 mos

      Plan, organize, control and evaluate IT and electronic data operations. Audit systems and assess their outcomes. Manage internal and outsourced IT staff by communicating job expectations and appraising their performance. Design, develop, implement and coordinate systems, policies and procedures. Ensure security of data, network access and backup systems. Act in alignment with user needs and system functionality to contribute to organizational policy. Identify problematic areas and implement strategic solutions in time. Manage user environment and integrate client-side help desk support Develop and manage annual budget and ensure cost effectiveness.

  • Director of IT at Third Rock Ventures
    Jun 2019 - Jul 2020 · 1 yr 2 mos

    Responsible for the management, strategy, and execution of IT infrastructure projects and supporting the creation of new companies. During my time at Third Rock Ventures I overhauled the on-premise infrastructure and migrated many services to SaaS offerings or into AWS. I assisted with on-boarding a new MSP into the company to manage our End User Support services and to act as an engineering bench to pull from for larger projects. I also organized the company's first IT steering committee to create and prioritize technology project ideas to proactively address issues within operations. When projects reached maturity, I helped with the launch of new companies. I guided the newly formed leadership team through the process of choosing core services, identifying business critical IT functions, and designing systems to support the scientific teams. I also helped with the initial office space and lab build outs as well as working with the computational biologists to create suitable AWS and Azure environments. This included infrastructure design, system requirement definitions, and the beginning of the companies IT SOP and policy documentation. - Worked with AWS engineers to be the first to roll out the new Biotech Blueprint which integrates security and compliance into the initial AWS setup for new companies. - Created a detailed IT cost breakdown to manage a first IT budget and provide data to the finance team for chargeback to project groups. - Updated networking equipment in all 4 offices to Cisco Meraki, simplifying the overall design and reducing support requests due to network related issues. - Reduced the reliance on physical server infrastructure by migrating email services to O365, shared network storage to cloud solution, and phone service to Zoom Phone off a legacy PRI system. - Analyzed and updated the WAN connection design to be more appropriately sized for the needs of the office, reducing overall cost and increasing service reliability.

  • Foundation Medicine (6 yrs 9 mos)
    • Associate Director, Cloud Operations, DevOps, Network Services, and Database Operations
      Mar 2018 - Jun 2019 · 1 yr 4 mos

      As a Product Owner for three separate teams, I had to balance the business demands and driving vision across these multiple areas of disparate technologies. I was responsible for ensuring the teams are focused on the “right” work and do not lose sight of the big picture. This required me to participate in project planning with all business units to effectively set estimates and scope work for each team to perform.

    • Associate Director, DevOps and Network Services
      Jun 2017 - Mar 2018 · 10 mos

      Leading the companies first DevOps team, tasked with building and supporting a comprehensive automation platform for the technology organization. Be a change leader and DevOps evangelist, playing a critical role in a new wave of collaboration within a siloed development and operational team structure. Additionally, manage the Networking team during a time of international corporate expansion and lab build outs. Advise on all network and collaboration projects from infrastructure and architecture design to telecommunications and WAN/LAN configuration. - Work with the Regulatory and Compliance teams to define new standards of environmental control using CI/CD pipeline - Design, build, and maintain the standardized CI/CD pipeline for all application deployments - Guide strategic decision making with regards to technology platform choices - Leading the project to redesign the network at HQ and support corporate expansion in 3 locations - Guided the transition of application support to the development teams - Supervise a 24/7/365 on-call rotation for support of all IT infrastructure - Act as the technical expert, educating various executive members and team leads on technology solutions

    • Associate Director, Network and Application Services
      Feb 2016 - Jun 2017 · 1 yr 5 mos

      - Acted as Interim Director of IT Operations from October 2016 – March 2017 - Built and managed an $8m technology department budget to support a 50% YoY growth of our team and project initiatives - Created a roadmap for the technology group to plan and communicate expectations to senior management - Led a project to build the first enterprise cloud infrastructure in the company - Responsible for infrastructure availability and stability - Manage geographically diverse, multidisciplinary teams - Led the initiative to build 2 international lab and office locations - Directly managed a project to migrate all existing application workloads from on-prem infrastructure into the cloud - Created and managed the first DevOps team in the company - Developed an automated software deployment pipeline - Led efforts to secure existing infrastructure and prepare for SOC, ISO, and HIPPA audits - Guided efforts to formally institute ITIL practices and standards within the technology group - Responsible for vendor negotiations, software licensing and infrastructure hardware procurement - Built a multi-site End User Compute support team for all tier-1 and tier-2 IT inquiries - Lead networking team in all architectural design, capacity planning, configuration, and deployment projects - Directed an acquisition of a lab facility and personnel. Created a comprehensive plan of action to convert employees and systems to FMI standards. - Revamped manual deployment process to prepare development teams for automated deployment pipeline - Develop team goals to align with corporate initiatives - Create monthly status slides for senior management team meeting - Guide strategic decision making with regards to technology platform choices - Coordinate project resources to meet corporate timelines - Support a HPC analysis pipeline and Isilon storage cluster - Supervise a 24/7/365 on-call rotation for support of all IT infrastructure - Act as the technical liaison for various business unit projects

  • Network Administrator at TSD Rental
    Jul 2012 - Oct 2012 · 4 mos

    - Worked with multiple Cisco ASA’s, Cisco switches, and Dell PowerConnect switches to maintain and expand a a large enterprise network environment - Worked with F5 Big-IP products to provide load balancing for web traffic requests - Worked with VMware and vSwitch to properly maintain a large, segmented network - Researched, installed, and maintained multiple network monitoring software solutions - Responsible for the scaling of the network to match the growth of the company - Expected to provide opinions on areas of improvement to maintain a secure yet accessible network - Maintained a large scale VPN network between multiple offices, datacenters, and customer locations - Ensured the network maintained PCI compliance - Worked with TSD product managers to ensure 100% availability to the core software products that our customers rely on - Provided technical insight on the architecture of the network

  • Thinking Phone Networks (Greater Boston Area)
    • Provisioning Network Engineer
      Sep 2010 - Jul 2012 · 1 yr 11 mos

      - Worked with Cisco routers, switches and ASA’s as well as Adtran routers and switches in a configuration and troubleshooting capacity on a daily basis - Utilized Linux based tools to manage virtual PBX’s and troubleshoot networking reports - Assisted customers with firewall configuration to support VoIP - Acted as the technical sales specialist on customer calls for all networking and service related questions - Worked directly with customers to design, implement, and support voice and data networks - Configured all networking equipment to meet the unique needs of every customer - Provided technical support for newly deployed customers - Trained customers on procedures and protocols of their new phone system - Performed onsite visits for new site turn ups, network upgrades and to troubleshoot any issues - Configured Asterisk call-flow behavior to meet customer requests - Managed customer call profiles in a virtual Linux environment

    • Support Engineer
      Nov 2009 - Sep 2010 · 11 mos

      - Provided support for all customer services including VoIP technology, networking, and our CRM and Web Portal solutions - Wrote technical manuals for both internal and external use - Managed the support ticketing queue, performing initial triage of all inquiries - Acted as the escalation point for all customer related reports - Worked with end users to troubleshoot and resolve any network issues - Managed call behavior of customer profiles in a Linux environment - Configured Asterisk to meet all customer expectations of call workflow - Collaborated with external IT teams to upgrade their existing voice and data networks