Carolina Tarantino

Stem Cell Biologist | Human Pluripotent Stem Cells, Organoids & CRISPR/Cas9 | Disease Modelling & Regenerative Medicine

Greater Barcelona Metropolitan Area

About

Stem Cell Biologist with a PhD in Molecular Medicine and over 10 years of experience in regenerative medicine and stem cell research. Specialized in human embryonic stem cells, patient-derived iPSC technologies, CRISPR/Cas9 genome engineering, and organoids for disease modelling and therapeutic development. Extensive experience in developing advanced human in vitro models, supporting national and international research collaborations, with particular expertise in brain, cardiac, and kidney organoids. Technical background combining stem cell biology with advanced molecular and cellular approaches, including genome engineering, gene regulation studies, and functional assays. Contribution to the establishment and coordination of research laboratories in international environments, supporting laboratory operations, experimental platform development, biosafety compliance, and collaborative research activities. Currently leading an independent research project focused on modelling Ataxia Telangiectasia using genetically engineered human pluripotent stem cells and brain organoids to investigate disease mechanisms and therapeutic strategies. Technical expertise includes: • Human pluripotent stem cell culture and differentiation • Brain, cardiac, and kidney organoids • CRISPR/Cas9 genome engineering • Disease modelling using hPSC • Molecular and cellular biology techniques • Research coordination and scientific training

Experience

  • Superior Research Technician at Institute for Bioengineering of Catalonia (IBEC)
    Aug 2015 - Present · 10 yrs 11 mos

    Contributed to research in regenerative medicine focusing on human pluripotent stem cells, organoids, and genome engineering. Lead responsibility for the design and execution of CRISPR/Cas9 genome editing experiments, generating 20+ genetically modified hPSC lines (knock-out, knock-in, and reporter models). Developed brain, cardiac, and kidney organoid systems for disease modelling applications. Contributed to multiple high-impact publications in regenerative medicine and developmental biology. Led an independent research project on Ataxia Telangiectasia using CRISPR-engineered hPSCs and brain organoids to investigate disease mechanisms and therapeutic strategies. Responsible for experimental design, genome editing workflows, organoid development, and coordination of collaborative research activities. Mentored and trained students and researchers in stem cell biology, genome engineering, and molecular biology techniques. Supported laboratory operations including workflow coordination, biosafety compliance, procurement, and infrastructure maintenance.

  • Superior Research Technician at CMRB
    Mar 2013 - Aug 2015 · 2 yrs 6 mos

    Supported multiple research projects in regenerative medicine and disease modelling using human pluripotent stem cells. Generated and characterised human iPSC lines from healthy donors and patients with disease conditions. Contributed to studies on Fanconi anemia pathogenesis and regenerative strategies. Participated in research on cardiac regeneration in zebrafish models. Developed and optimised differentiation protocols for oligodendrocytes from hPSCs. Gained experience in stem cell reprogramming and organ-specific differentiation systems.

  • Research contract at CEINGE Biotecnologie Avanzate
    Mar 2010 - Dec 2010 · 10 mos

    Conducted research on miRNA-mediated regulation of embryonic stem cell fate. Investigated the role of miR-125a in mouse embryonic stem cells within the SIROCCO EU-funded project. Performed molecular biology and gene regulation studies in early stem cell systems.