Trieste, Friuli-Venezia Giulia, Italy
With over 15 years of experience in the pioneering field of In Silico Trials, I am passionate about the use of cutting-edge computational modeling and simulation for the design, development, and regulatory assessment of new medical devices and personalized treatments. As Senior R&I Project Manager at InSilicoTrials, I contribute to numerous EU-funded R&I projects aimed at developing innovative medical technologies, in collaboration with academic, clinical and industrial partners. I support the company's vision of democratizing modeling and simulation in healthcare and increasing the pace of innovation by combining scientific, technological, and regulatory know-how. I work in a multidisciplinary team of researchers, engineers and developers, and collaborate with internal and external stakeholders to ensure the quality, usability, and reliability of our cloud-based computational hub, InSilicoTrials.com. I also hold the PRINCE2® and AgilePM® certifications, which demonstrate my skills in project management and agile methodologies.
I am responsible for establishing and coordinating strategic partnerships across Europe and US, in collaboration with academic, clinical, industrial and regulatory stakeholders; writing, submission and management of EU- ad US- funded R&I projects aimed at developing innovative medical technologies, with focus on the use of modeling and simulations for the development and regulatory evaluation of new medical products. Main activities: Manage and coordinate activities within EU- and US- funded Research and Innovation (R&I) projects; design computational solutions to evaluate new medical products; plan and manage simulation campaigns; design cloud-based Decision Support Systems (DSS) and Software-as-Medical-Devices (SaMD); lead product development teams; regulatory research related to in silico trials; manage innovation property rights and define exploitation roadmaps; review and write scientific, technical, regulatory, and legal documentation; prepare technical and financial review reports. Main EU-funded R&I Projects: • In Silico World - Lowering barriers to ubiquitous adoption of In Silico Trials (Jan 2021 – Dec 2024) • SimCardioTest - Simulation of Cardiac Devices & Drugs for in-silico Testing and Certification (Jan 2021 – Jun 2025) • BRAINTEASER - BRinging Artificial INTelligencE home for a better cAre of amyotrophic lateral sclerosis and multiple SclERosis (Jan 2021 – Jun 2025) • EDITH – Ecosystem for Digital Twins in Healthcare (Oct 2022- Dec 2024) • METASTRA – Computer-aided effective fracture risk stratification of patients with vertebral metastases for personalized treatment (Jul 2023 – Jun 2028) • SMASH-HCM - Stratification, Management, and Guidance of Hypertrophic Cardiomyopathy Patients using Hybrid Digital Twins (Jan 2024 – Dec 2028) • DeCODe - Develop Child and Orphan Device Evaluation (Sep 2024-Aug 2026)
During my research activity, I developed a new personalizable musculoskeletal model of the lower extremity, integrated with medical imaging data (CT, MRI and PET), to be used by surgeons in a virtual reality system to simulate complex orthopedic operations. This research was carried within the TLEMsafe project, funded by the European Union, in close collaboration with several international partners, such as Radboud University Medical Center (Nijmegen, The Netherlands), Warsaw University of Technology (Warsaw, Poland), AnyBody Technology A/S (Aalborg, Denmark), Materialise NV (Leuven, Belgium) and Brainlab AG (Munich, Germany).
As Project Manager for the international TLEMsafe consortium, I was responsible for coordinating activities of the partners, organizing project meetings, communicating with the European Commission project officers, preparing scientific, financial and management reports for annual reviews, as well as evaluating risks and commercial exploitation, and disseminating project results to healthcare stakeholders and laymen audience.