Erembodegem, Flemish Region, Belgium
After 4 years in Technical Service supporting Flow Cytometry customers from around Europe, I have decided to put my knowledge at the service of our Benelux team. My daily activity consist in supporting our sales department in their daily contact with our customers. Developing marketing material and defining new strategies to promote our broad biosciences portfolio (while monitoring the market) is my focus. My mission is to provide all the tools that our customers need to advance the world of health.
Topic: Development of single-domain antibodies (Nanobodies) for cancer immunotherapy • Tumor induction and processing in mice 1. Cancer cells culturing 2. Subcutaneous mouse injection 3. Tumor processing and cell analysis (Flow cytometry/Cell sorting) 4. Primary cells culturing and stimulation • Generation and characterization of Nanobodies 1. Panning, screening, and recloning of a Nanobody library. 2. Nanobody characterization (SPR-based assays). 3. Functional selection of Nanobodies (HUVEC’s collapse assay). 4. Nanobodies’ in vivo biodistribution (SPECT-CT scan). 5. Assessment of Nanobodies’ therapeutic potential. • Designing, performing, and analysis of wet lab experiments • Validation and optimization of cell functional assays • Coordinating several collaborators for the success of the project • Training and guiding technicians and master students • 1 first author publication in a peer reviewed journal (IF: 3.9), 2 co-author publications in a peer reviewed journal (IF: 13.25 and 4.2)