Audrey GABELLE

Preventive Neuroscience & Digital Health Leader Brain Health • Precision Prevention • Biomarkers • AI & Digital Medicine

Greater Montpellier Metropolitan Area

About

Driving patient-centric innovation in brain health, Alzheimer’s disease, and neurodegenerative disorders—de-risking and accelerating pharma and biotech development Physician–scientist and Professor of Neurology (MD, PhD) with over 15 years of experience in brain health, neurodegenerative diseases, biomarkers, and precision prevention. Trained as a cognitive and behavioral neurologist, I specialize in early diagnosis, patient stratification, and personalized approaches to Alzheimer’s disease and related disorders, with a strong focus on clinically meaningful and patient-relevant outcomes. I work at the intersection of clinical development, digital health, and translational neuroscience, supporting pharmaceutical and biotechnology companies in the design, execution, and optimization of drug and digital development programs. My experience spans the full clinical development continuum—from phase I to phase IV trials—including endpoint selection, biomarker strategy, digital endpoints, patient enrichment, and real-world evidence generation, with the objective of improving patient experience, relevance, and adoption. I have led and advised European and international academic–industry partnerships, helping translate advanced neuroscience, biomarkers, and AI-driven tools into regulator-relevant and patient-centric solutions. My areas of interest include disease-modifying therapies, early intervention, prevention strategies, and targeted treatments, where aligning scientific rigor with patient needs and real-world feasibility is critical to success. Previously, I held a senior leadership role at Biogen Digital Health (US), working on digital screening tools, personalized medicine strategies, and the integration of digital and biological data to support targeted drug development in Alzheimer’s disease and neurodegenerative disorders. Alongside my academic and hospital leadership roles—including managing specialized memory centers and serving as President of a national network of over 400 memory clinics—I provide senior consulting and advisory support to pharmaceutical companies, biotechs, and health-tech startups, focusing on de-risking development programs and accelerating time to patient impact. Open to advisory and consulting engagements with pharma and biotech teams committed to patient-centric innovation in brain health and neurodegenerative diseases.

Experience

  • CHU Gui de Chauliac, Montpellier (24 yrs 8 mos)
    • Neurologue et Docteur en Neurosciences
      Nov 2001 - Present · 24 yrs 8 mos

      Expérience clinique dans le domaine des affections neurodégénératives (maladie d'Alzheimer et syndromes apparentés) et en particulier des troubles cognitifs et comportementaux. Expérience dans le domaine de la recherche clinique des biomarqueurs diagnostiques et pronostiques de la maladie d'Alzheimer et syndromes apparentés et en recherche expérimentale. Cours magistraux à l'Université de Montpellier I, formation des professionnels de santé, conférences grand public...

    • Professeur des universités-Praticien Hospitalier de Neurologie
      Sep 2019 - Present · 6 yrs 10 mos

    • PHU de Neurologie
      May 2011 - Sep 2019 · 8 yrs 5 mos

      Le Centre Mémoire de Ressources de Recherche (CMRR) du CHRU de Montpellier a été labellisé en 2002. Il est localisé au sein du Département de Neurologie de l’hôpital Gui de Chauliac. Le CMRR de Montpellier est impliqué au niveau local, départemental, régional et inter-régional, dans le champ des soins, de l'enseignement, de la recherche et de la mise en place de Réseaux. A ce titre, le CMRR de Montpellier participe à de nombreuses collaborations dans des projets de Recherche nationaux, européens et internationaux.

  • Lead Digital Research and Personnalized Medicine in Alzheimer at Biogen
    Dec 2021 - Dec 2023 · 2 yrs 1 mo

    Amazing experience in Biogen Digital Health (Cambridge, US) working on digital screening tools at population level in collaboration with Apple (Intuition study), developping personalized medicine for targeted drugs (DMT) in AD and prevention/predictive AI models.

  • Maître de Conférence des Universités - Praticien Hospitalier de Neurologie at CHRU de Montpellier
    Nov 2014 - Sep 2019 · 4 yrs 11 mos

    Responsable du Centre Mémoire de Ressources et de Recherche et de l'unité de Neurologie Comportementale au sein du Département de Neurologie du CHRU de Montpellier, Hôpital Gui de Chauliac.