Greater Boston
PhD Bioinformatics Scientist with 7+ years of experience creating and analyzing omics data. Diverse experience working with large, multimodal bulk and single cell datasets. Excels at working with bench and computer scientists alike due to wet and dry lab experience.
-Created the first integrated multiomic chromatin map of cellular senescence (RNA-seq, long-read DNA-seq, methylation, Hi-C data). -Together with a team of statisticians developed and improved a novel elastic shape analysis methodology, which identifies prototypical shapes in 3D chromosome structures, facilitating exploration of their biological roles. -Launched an ongoing project on rejuvenation of aged mice by creating and analyzing a single-cell multiomic (scRNA-Seq and scATAC-Seq) dataset. -Benchmarked a novel Topologically Associating Domain (TAD) caller, which allows tunable hierarchical calling, to indicate its performance was equivalent to other state-of-the-art TAD callers.
-Prepared patient tumor DNA samples and performed sequencing of them on Illumina HiSeq platforms. -Led implementation of Qubit assay and automated RNA sequencing platform. -Completed independent computational projects to improve wet lab efficiency.
Undergraduate teaching assistant for Organismal Biology (Biocore 486) and Cellular Biology (Biocore 384) labs.
-Researched the ability of rice to detect bacterial signaling molecules by deleting nod genes. -Lead programmer on development and validation of Python script for phylogenetic analysis of Agrobacterium genus speciation, leading to implementation for all lab phylogeny analysis.
-Analyzed lncRNA MEG3 structure to determine if there was evidence of conserved structure. -Developed general methodology to assess conservation of lncRNA secondary structure.