Bengaluru, Karnataka, India
Recognized for clinical and large animal preclinical work, model and protocol development, and medical image interpretation and analysis. Proven ability to conduct literature and regulatory searches; organizing and assimilating search results; design of experiments; data acquisition, analysis and interpretation; development of measurement techniques and models for clinical feasibility studies; development of computational algorithmic methods for processing and analysis of genomic data. Exceptional communicator and project leader with strong detail, organization and time management skills able to prioritize and direct simultaneous assignments in demanding environments. Independent contributor and thought leader often called upon to provide cross functional support beyond the scope of basic job functions.
Managed epidemiologic and pharmacovigilance real-world data and evidence (RWD/RWE) analyst teams for US pharma and medical device clients in Engagement Manager role. Maintained weekly/monthly quality and efficiency metrics for 150-member data scientist team for Account Governance.
Co-founded APT, an early-stage company with the goal of increasing treatment options for cancer patients using computational methods to analyze and interpret patient-derived whole-genome expression (RNA) data. Managed all aspects of product development, including program optimization, user interface, and data security. Initiated and supervised clinical studies at multiple cancer centers. Executed business plan and managed personnel of diverse backgrounds.
Managed preclinical large animal study including protocol development and study execution for quantitative comparison of implant prototypes. Conducted gap analysis for updated ISO 10993 medical device biocompatibility compliance standards and generated compliant test report documentation. Analyzed clinical literature [medical journals, clinical trials and public records] and interviewed key physicians to identify and report potential therapy development opportunities. Assisted in the development of market research survey for end users and overall evaluation of survey results.
Contributed to the development of preclinical animal testing of minimally invasive percutaneously-implanted cardiac annuloplasty device. Created methods and protocols for bench testing of implantation device components. Helped formulate procedural methodology. Conceived imaging-intensive process flow for percutaneous implantation using sub-xiphoid approach. Presented innovative MSCT image analysis methodology to senior management. Utilized anatomical and vascular landmarks for patient specific pre-procedural planning of device implantation. Drove the development of a standardized quantitative tool to screen patients for inclusion in clinical implant trials based on echocardiographic/clinical criteria. Provided didactic anatomical and imaging-specific training for cardiothoracic surgeons and interventional cardiologists, and participated as proctor-in-training during clinical case work. Facilitated communication between echocardiographic personnel at clinical trial centers and the Core Lab as internal echo expert.
Technical Lead at Echocardiographic Image Processing Lab, Feinberg Cardiovascular Research Institute. Overall responsibility for technical aspects of research studies. Maintained data acquisition, image processing systems and software. Supervised lab personnel. Developed and implemented sound experimental protocols for bench, animal and clinical studies. Helped assemble and submit grant applications to nonprofit funding agencies and corporate sponsors. Prepared manuscripts for submission to peer-reviewed journals. Created poster and slide presentations for scientific meetings. Developed literature for various audiences and grant funding agencies. Honed communication and interaction skills with cardiologists and specialized healthcare providers, collaborative research groups and partnerships with other educational institutions and private companies. Coordinated tech support and all media functions for Echo Northwestern - 4 day CME course on advances in echocardiography.