United States
Scientist with a proven track record in assay development for early drug discovery. Experience with cellular and chemical assays for early portfolio projects in the pharmaceutical industry. Focused on assay development of high throughput screening protocols, ADME assessments, and mechanism-of-action deconvolution techniques for metabolic, immunologic, and neurologic diseases. Current research focus on the therapeutic potential of neurotrophic factors for Parkinson's disease and the prospects of using microglial therapies against Alzheimer's disease. Co-founder and former COO of Women Empowerment Through Education, a global non-profit organization created to help provide better educational opportunities for women in remote areas of the developing world. Consultant for organizations in the start-up phase focusing on business development, industry establishment, and organizational management. Graduate education at the University of Wisconsin, Madison class of 2022. M.S. degree in Biotechnology with a focus on business development, regulatory frameworks, and scientific research and development. Completed coursework related to biotechnology regulations, intellectual property management, biotechnology operations and logistics, project management and effective leadership, commercialization pathways, business growth and sustainability, early drug discovery, diagnostic testing, biomanufacturing, and assay development. Thesis focus on iPSC-derived CAR-NK (CAR-iNK) cells as an immunotherapy for PD-1L-targeted triple negative breast cancer. Undergraduate education at Elmira College class of 2020. B.A. degree with a double major in Psychology and Biology. Investigated research principles in cognitive psychology by evaluating the relationship between emotion regulation and anger management as well as decision-making properties in the disinformation age. Conducted laboratory work in biochemistry by delineating the chemical characteristics of protein 3H04 and updated the findings to the Protein Data Bank. NCAA collegiate athlete on the men’s varsity golf team. Resident assistant and campus tour guide for three consecutive years. Inducted into three honor societies and elected President of the Psi Chi (Psychology) and Omicron Delta Kappa (Leadership) honor societies. Graduated with summa cum laude honor distinctions.
Providing instructional lectures and one-on-one tutoring sessions for students in the sciences and humanities fields. Reviewing research papers and assignment templates to assist with course preparations. Instructing in courses related to Cell Biology, Microbiology, Cancer Biology, Anatomy & Physiology, Genetics, Molecular Biology, Immunology, Neuroscience, Cognitive Psychology, and Developmental Psychology.
Conducted and analyzed data for liver microsome stability, thermodynamic solubility, and plasma-protein binding assays in a high-throughput environment as part of the ADME team. Validated small molecule drug candidates for therapeutic potential on obesity-associated disorders. Utilized a Sciex QTRAP LC/MS system to analyze samples and to progress compounds to the next stage of the drug discovery process.
Conducted high throughput screening assessments of enzyme activity assays to validate compound safety and efficacy against disease models of metabolic dysfunction-associated steatohepatitis (MASH). Performed in vitro ADME screenings like enzyme activity assays, cytotoxicity assays, protein binding assays, and cross-reactivity assays to evaluate PK and PD properties, to screen for off-target effects, and to determine dosage optimizations and IC50 values. Cultured, maintained, and analyzed primary hepatocytes and hepatic stellate cells for compound safety screenings. Evaluated biomarker assessment studies for signs of fibrosis, inflammation, and hepatic steatosis. Validated gene expression studies via AAV transduction and qPCR methods on AML-12 OE cell models.
Consulting business focusing on business development, industry establishment, and organizational management. Specializing in document drafting, technical writing, project management strategy, and project model formulation. Targeting emerging businesses in the start-up phase as well as expanding businesses to help with growth, scale-up, and sustainability.