Basel, Basel, Switzerland
As a dedicated professional with a robust background in field science, analytical methodologies, and quality assurance/control within the industry, I bring a wealth of expertise to every project. My key strengths include: Field Science Expertise: Proven experience in conducting comprehensive field research and data collection, ensuring accurate and reliable results. Analytical Proficiency: Skilled in utilizing advanced analytical techniques to interpret complex data, driving informed decision-making processes. Quality Assurance and Control: Demonstrated ability to implement and oversee QA/QC protocols, maintaining the highest standards of product and process integrity. Problem-Solving Aptitude: Adept at identifying challenges and developing innovative solutions to enhance operational efficiency and effectiveness. Collaborative Team Player: Strong interpersonal skills with a track record of working seamlessly with cross-functional teams to achieve organizational objectives. I am actively seeking opportunities to leverage my skills and experience in roles such as Automation Scientist, Analytical Expert, or QA/QC Specialist within dynamic industrial settings. My commitment to excellence and continuous improvement positions me as a valuable asset to organizations striving for operational success and innovation.
- Conduct solid-state characterization and developability studies to support small-molecule drug development and pre-formulation programs across early and late discovery phases. - Design and execute high-throughput salt screening, polymorph screening, and crystallization experiments using automation platforms, enabling rapid and data-rich decision-making. - Perform automated dissolution and solubility studies to assess solid-form performance under physiologically and formulation-relevant conditions. - Operate, optimize, and maintain laboratory automation workflows, including experimental design, method setup, troubleshooting, and performance verification. - Analyze solid-state screening outputs to identify optimal salt forms, crystalline phases, and formulation candidates based on stability, solubility, and manufacturability. - Carry out liquid chromatography (LC/HPLC) analyses for quantitative evaluation of samples generated from automated and manual solid-state studies. - Develop, adapt, and validate analytical methods to ensure accurate, reproducible, and high-throughput data generation. - Interpret chromatographic and solid-state data, perform data trending and quality checks, and clearly communicate results to project teams. - Collaborate closely with medicinal chemistry, formulation, DMPK, and project teams to translate solid-state insights into actionable development strategies. - Document experimental workflows, analytical methods, and results in accordance with internal quality standards and best laboratory practices. - Contribute to continuous improvement of automation protocols, experimental throughput, and data robustness within the solid-state and analytical laboratories. - Support technology transfer, knowledge sharing, and onboarding related to automated solid-state and analytical workflows.
- Antibody Conjugate Design: Engineered an innovative antibody conjugate using nanoparticulated Zeolite Imidazolate Frameworks (ZIFs), a subclass of Metal-Organic Frameworks (MOFs), for applications in immunoassays and ELISA. - Fluorescent MOF Development: Synthesized a novel ZIF-90 derivative incorporating a covalently bound pyrene fluorophore. This functionalized MOF enables fluorescence-based quantification of short-chain phthalates through quenching effects. Additionally, colloidal particles of the modified ZIF-90 were successfully obtained. - HPLC Methodology Optimization: Developed a new HPLC sample preparation and quantification methodology to precisely determine the chemical composition of modified ZIFs. - Analytical Techniques Expertise: Proficient in key analytical techniques, including Nuclear Magnetic Resonance (NMR), X-ray Diffraction (XRD), and UV-Visible Spectroscopy (UV-Vis), with experience in knowledge transfer and training. - HPLC Method Development: Designed and optimized an HPLC method for analyzing small organic molecules, integrating comprehensive data analysis capabilities. - Organic Synthesis in MOF Functionalization: Extensively employed organic synthetic pathways, including Schiff base condensation reactions and post-synthetic reductions, to functionalize MOFs for targeted applications (e.g., pyrene incorporation into the imidazole framework). - Specialization in Analytical Chemistry, Organic Chemistry, and Material Science: Strong expertise in Analytical Chemistry, Organic Chemistry, and Material Science, with a focus on MOF synthesis, characterization, and functionalization.
- Quality Control and Product Analysis: Conducted quality control on finished products and performed daily product analysis to ensure compliance with standards in a GMP environment. - Quality Control and Quality assurance responsibilities: responsible for the compliance of GMP guidelines, REACH and ADR during all steps of operation - Product Development: Developed two new products (fabric softener and air freshener) and modified two product formulas within a three-month timeframe. - Safety Data Sheets (SDS) and Label Compliance: Maintained Safety Data Sheets (SDS) and product labels in accordance with REACH and CLP regulations. Authored two SDS documents. - ISO 9001 Quality Management System: Assisted with the implementation of the ISO 9001 Quality Management System, contributing to enhanced quality control processes. - Auditing Experience: Conducted internal audits and participated in certification audits led by Bureau Veritas. - Gained knowledge of process development and a high technical understanding of chemical processes on industrial level