Ath, Walloon Region, Belgium
Exited by new challenges, I am interested in problem solving tasks and in implementing projets. My technical background is my current tool box, providing the resources required to help my team to reach the defined targets. My management style is based on trust, communication and the well known expression: lead by example.
The score of action as supervisor I is extended to : - The micro lab for digitalization & equipment validation & maintenance - CAPEX writting and management of resources - Internal auditor
Manage a team of around 10 people working on a variety of subjects : - from routine tasks (on-going stability, life cycle management on instruments & methods) - to improvement projects (implementation of softwares/strategies towards a paperless lab, increase efficiency and maintain compliance) - via remediation projects such as investigations to understand the issues the lab go through & implementation of the required actions This team is there to support the QC Lab to release products safely and on time for our patients.
Identify improvements, implement solutions in cGxP environment. Compliance: - Identify & prevent gaps by developing & implementing functional & automatic solutions in cGxP environment - Owner & approver of non conformity, CAPA, lab investigations - Highly involved in audits. Optimization: - Instore laggings & leading Key Performance Indicators - Identify & implement solutions to continuously improve lab work/workload - Wrote/modify Standard Operating Procedures. Management & communication: - Supervise contingent lab/student placements. - Team work with different levels of responsibilities & across-departments - Organize & lead meetings.
Biocatalytic process development in cGMP environment for large scale manufacture. Process development and analytic: - Reverse engineering - Enzyme immobilization - Solid support chemistry - Understand and improve process using a QbD approach (Design of Experiment) - Develop and implement analytical methods Project management: - Organize and animate meetings - Define and organize experiments - Mentor junior members - Write reports Communication: - First point of contact to customers - Promote knowledge via presentations and discussions Health and safety: First Aid at work
cGMP, TSE/BSE free & non-GMP synthesis of [14C]- and/or stable labelled active pharmaceutical ingredient; custom synthesis – quote writing. Chemistry: - cGMP and non-GMP syntheses of stable and [14C]-labelled compounds, in a regulated environment. - Custom synthesis. - Source of scientific propositions to complete project on time and for future optimizations. Analytical work: - Release analyses for non-GMP pharmaceutical compounds (including NMR and HPLC analyses). - Help in the writing of specifications for cGMP materials. Customer focus: - Provide bimonthly updates (via e-mails and phone calls) as well as final and campaign report. - Projects performed in a timely fashion. Project Management: - Contribute to the technical assessment of the enquiries. - Participate to the quotation writing process (including pricing). - Order chemicals. - Organize shipment. - Manage storage agreements. Quality system: - Raise quality events - Revise Standard Operating Procedure Health and Safety: - Driving force for the implementation of a contingency emergency plan in the radio-laboratory. - Knowledge of the procedures for treatment and shipment of radioactive wastes. - First Aid at work. - Radiation Protection Supervisor
Custom synthesis, non-GMP synthesis of stable & [14C]-labelled active pharmaceutical ingredient. Chemistry: - Synthesise stable and [14C]-labelled compounds in a regulated environment (SOP and cGMP environment). - Custom synthesis. - Source of scientific propositions to complete project and for future optimizations. Analytical work: Release analyses for non-GMP pharmaceutical compounds. Customer focus: - Provide bimonthly updates as well as final report. - Perform projects in a timely fashion. - Contribute on the technical assessment of the enquiries. Health and Safety: - Invested in the implementation of the emergency procedures in the radio-laboratory. - Knowledge of the procedures for treatment and shipment of radioactive wastes. - First Aid at work.
Design, synthesis and characterization of 10 bio-based monomers derived from carbohydrate or ferulic acid. Develop conditions to polymerize 4 of them into natural, biodegradable polycarbonates or polyphosphoesters. Determination of their spectroscopic, thermal, photophysical and nanomechanical properties as well as their degradation over time. Graft copolymers have been developed from the same monomers to generate fluorescent degradable micelles. (Pr. Wooley)
Synthesis of β-lactones and β-thiolactones (about 20 targets within 3 to 10 synthesis steps). Thermic, kinetic and reactivity toward nucleophiles studies. Synthesis of N-acetylneuraminic acid derivatives, C- and S-glycosylations studies. (Pr. Crich) Bachelor level teaching (organic chemistry, 192 hrs): organization, knowledge transmission, teaching skills, motivate students.