Alexandre Leclair

Senior Expert Science & Technology

Switzerland

About

Experience

  • Senior Expert Science & Technology at Novartis
    Jul 2022 - Present · 4 yrs 1 mo

  • PhD thesis at Ecole polytechnique fédérale de Lausanne
    Oct 2017 - Dec 2021 · 4 yrs 3 mos

    - Synthesized and investigated the remote C(sp3)-H functionalization of several redox-active alcohol derivatives - Developed an iron catalyzed C(sp3)-H azidation of N-acyloxy imidates for the synthesis of β-azido alcohols - Underwent synthetic studies toward the total synthesis of decursivine through photoredox catalysis - Discovered and optimized a photoredox-catalyzed two-carbon ring expansion of cyclobutanols to cyclohexenones and applied it to a total synthesis of uleine Under the supervision of Prof. Jieping ZHU, LSPN, EPFL

  • Master's thesis in methodology at Ecole polytechnique fédérale de Lausanne
    Feb 2017 - Aug 2017 · 7 mos

    - Optimized a copper catalyzed oxidative alkoxycarbonylation of olefins. Under the supervision of Prof. Jieping ZHU and Balàzs BUDAI, LSPN, EPFL

  • Research Intern at The Janssen Pharmaceutical Companies of Johnson & Johnson
    Mar 2016 - Aug 2016 · 6 mos

    Six-month internship in the Active Pharmaceutical Ingredients Small Molecules Research and Development department Under the supervision of Dr. Sébastien LEMAIRE and Dr. Xavier JUSSEAU Development and optimisation of Friedel-Crafts type reactions on specific substrates

  • Research Intern at Laboratoire de recherche CEISAM (UMR 6230: CNRS et Université de Nantes)
    Jun 2015 - Jun 2015 · 1 mo

    - Optimized a palladium-catalyzed Heck-Matsuda reaction. One-month voluntary internship - Under the supervision of Dr. Françoise ZAMMATTIO and Dr. Mireia RODRIGUEZ I ZUBIRI