Alexandra Rausch

Principal Scientist in Cross Indication Research at Nuvisan ICB GmbH

Berlin Metropolitan Area

About

Experienced Lab Head with history of working in pharma industry since 2005. Strong research professional skills in Arthritis (RA, PsA), IBD,Psoriasis, Atopic Dermatitis, MS and SLE (in vivo & in vitro). Project leadership. Coping with multiple interfaces (e.g. clinical development, commercial, legal, chemistry). Team lead experience >19 years.

Experience

  • Lab Head in Cross Indication Research at Nuvisan ICB GmbH at Nuvisan ICB GmbH
    Jul 2020 - Present · 6 yrs

  • Bayer Pharmaceuticals (Berlin, Deutschland)
    • Lab Head in Indication Expansion
      Jan 2015 - Jul 2020 · 5 yrs 7 mos

      - in vitro & in vivo characterization of several drug development candidates (small molecules & biologics) with focus on autoimmune diseases, such as Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Psoriasis, Multiple Sclerosis and SLE - project leadership (from preclinical target validation up to start of clinical development) - pharmacology representative in Global Project Teams, Early Clinical Teams, Due Diligences, Target Product Profile generation - dealing with multiple interfaces (clinical development, commercial, etc.) and external networks (e.g. CROs, KOLs) - leadership of animal experiments - team lead of lab technicans, students and trainees

    • Lab Head in CMR Inflammation
      Sep 2011 - Dec 2014 · 3 yrs 4 mos

      - identification of new targets (biologics) for the treatment of Inflammatory Bowel Disease - antibody evaluation in in vivo models of inflammation and IBD - establishment of in vitro antibody screening assays and of new in vivo models - management of collaborations with external partners - leadership of lab technicans, students and trainees

    • Lab Head in Common Mechanism Research
      Nov 2007 - Aug 2011 · 3 yrs 10 mos

      - identification of new potential indications for drugs in development pipeline - target evaluation (in vivo & in vitro) of small molecules for treatment of Inflammatory Bowel Disease - establishment of in vivo models for IBD or pharmacodynamic models - leadership of lab technicans, students and trainees - leadership of animal experiments - management of collaborations

  • PostDoc at Schering
    Apr 2005 - Oct 2007 · 2 yrs 7 mos

    establishment of novel in vitro & in vivo models, characterization of drug candidates in different inflammation models related to dermatology (psoriasis, atopic dermatitis)

  • PhD at Research Center Borstel
    Mar 2002 - Feb 2005 · 3 yrs

    PhD in Immunology/Infection Biology (Interleukin-15, Immunity to Mycobacterium tuberculosis, vaccination studies, T cell immunity)