Basel, Switzerland
I'm a postdoctoral research scientist striving to gain insight into biophysical cell processes by developing synthetic enzymes and proteins built from DNA. With over 8 years of interdisciplinary research experience (physics, biology, chemistry), my expertise includes: • a broad range of biophysical & biomolecular analysis techniques • scientific accomplishments (5 high-impact publications, 13 conference contributions, 2 poster awards, 3D printing) • data analysis & interpretation • independent & collaborative problem solving I thrive on developing innovative solutions to complex problems with applications in biotechnology and biomedicine. Currently, I'm seeking to develop molecular diagnostics techniques that have a tangible impact on global healthcare challenges. As the next step in my professional career, I'm specifically interested in the biotechnology, healthcare, life sciences and pharmaceutical sector in Germany.
Project Manager for the development of clinical chemistry tests & immunoassays to assess the inflammatory status of patients.
• Development of synthetic enzymes and proteins built with DNA nanotechnology • Analyzing the interactions of molecular targets in plasmonic hotspots • Establishing a novel sensor for virus diagnostics • Coordinating research projects and uniting expertise across 2 interdisciplinary teams
• Design of protein-mimicking DNA nanostructures as a new class of therapeutics • Pioneered the application of DNA to control a cell membrane’s lipid composition by designing a synthetic enzyme that outperforms its natural protein analogue • Demonstrated its potential to induce cell death in human cancer cells • Managed projects yielding 5 high-impact publications with international collaborators
Designed & characterized protein-mimicking, DNA-built ion channels
Quantifying motor protein cargo transport using DNA nanotechnology (Prof Stefan Diez) • Protein & DNA handling and analysis with: TIRF microscopy, AFM, TEM, gel electrophoresis • Chemical modification & purification of DNA
Developed a controllable “DNA origami” cargo to quantify motor protein transport
Developed a signal-driven vesicle tethering system using DNA nanotechnology (Prof Ralf Seidel)
Studied 1D diffusion along DNA using DNA origami (Prof Ralf Seidel)