Louisville Metropolitan Area
My lab continues to explore the toxicological and pharmacological activity of chemicals through computational structure-activity relationship modeling. Virtual screening Computational chemistry Structure–activity relationship [SAR] Fragment-based modelling Predictive toxicology Virtual ligand-protein interactions Anticancer SAR models
Our cat-SAR® program develops chemical fragment-based SAR models from categorical biological response data. It is a reliable and cost effective means to predict a range of toxicological or pharmacological endpoints. cat‐SAR® is flexible and completely open with every detail of modeling transparent to the user.
Department of Medicine James Graham Brown Cancer Center
Department of Environmental Studies School of the Coast and Environment
Department of Environmental and Occupational Health Graduate School of Public Health