Akash Macha

Computational Biology + Biology at CMU

Basking Ridge, New Jersey, United States

About

Experience

  • Undergraduate Student Researcher at McManus Lab
    May 2024 - Present · 2 yrs 2 mos

    Analyzing ribosome profiling (Ribo-Seq), DNA sequencing, and genomic datasets of C. Neoformans to evaluate the transcription probability of non-canonical open reading frames (ORFs) via comparison of Ribo-Seq read distribution, periodicity, and magnitude at certain genomic positions to canonical ORFs through graphical visualizations (R) and machine learning models (Python).

  • CMC Management and Operations Intern at Daiichi Sankyo US
    Jun 2024 - Aug 2024 · 3 mos

    As a CMC Management and Operations intern I was tasked with creating a tool in Excel that compiled process parameter data across monoclonal antibody, drug substance, and drug product production for multiple batch records. I also utilized typescript, Excelscript, and VBA to create automated and user-prompted macros that allow for graphical data comparison of multiple process parameters across user-specified batch records. Additional responsibilities included professionally communicating with colleagues and mentors, gaining an in-depth understanding of each step of the antibody drug-conjugate production, creating an intuitive and easy-to-use user interface, and presenting the tool to colleagues and mentors from a variety of departments.

  • Treasurer and Vice President at Ridge Red Cross Club
    Sep 2021 - Jun 2023 · 1 yr 10 mos

    As the Treasurer helped to organize, finance, and promote donation drives. During the fundraiser events, spent multiple hours buying and preparing materials, making flyers, assigning roles to all of the club members that had signed up for the fundraiser, coordinating with teachers, and tracking the finances of the fundraiser. All of the proceeds of the fundraiser went to the American Red Cross. Currently serving as the Vice president of Red Cross Club.

  • Project Intern at Memorial Sloan Kettering Cancer-Center
    Oct 2021 - Oct 2022 · 1 yr 1 mo

    Research Internship at Memorial Sloan Kettering Center (MSKC), NY Sep 2021 - Current Interning at Cancer genomic laboratories of Dr. Nicholas Schultz to continue the research work conducted as a summer intern. Key areas of focus: ● Assimilating large exon splicing events data ● Analyzing the effects of exon splicing events ● Applying machine learning to predict the results of exon splicing events

  • Summer Intern at Memorial Sloan Kettering Cancer Center
    Jul 2021 - Aug 2021 · 2 mos

    Summer Internship at Memorial Sloan Kettering Centre (MSKC), NY June - Aug 2021 Among the top 1% of students selected for a prestigious 8-week paid research internship held at MSKC by the HOPP program. Completed internship at Cancer genomic laboratories of Dr. Nicholas Schultz. Key accomplishments: ● Assimilated large cancer data ● Expanded the cancer genomics database using cBioPortal ● Applied coding skills to address issues in cBioPortal ● Oral presentation and project reports