Barcelona, Catalonia, Spain
Enthusiastic and proactive biomedical scientist with extensive expertise drug discovery and oncology. Skilled in translating complex scientific data for diverse audiences and fostering collaboration across multidisciplinary teams. Experienced in project coordination, prioritization, and multitasking within deadline-driven environments. Passionate about advancing drug development against critical cancer targets to improve patient outcomes and deliver meaningful scientific impact.
o High-expertise in molecular and cellular biology assays to advance drug discovery campaigns against relevant cancer targets, operating within regulated environments aligned with best scientific practices. o Collaborate closely with multidisciplinary teams, including chemists, clinicians, and industry partners, to ensure alignment with cross-functional project timelines and deliverables. o Deepen expertise in oncology drug development and regulatory frameworks through targeted courses (UC San Diego | Coursera), integrating this knowledge to accelerate translational research. o Secured funding through two highly competitive national grants (Juan de la Cierva Formación & Postdoctoral AECC), demonstrating strong grant-writing, scientific planning, and project leadership skills. o Driven preparation of critical scientific documentation, including protocols, grants, and reports, ensuring accuracy, compliance, and clarity to support funding and regulatory submissions. o Execute comprehensive large-scale data analyses using Excel, Python (MIT | EdX certified), and R - performing statistical testing and trend analysis to inform strategic project decisions. o Skilled in synthesizing data from multiple sources and provide expert manuscripts reviews for high-impact scientific journals, maintaining a cutting-edge understanding of evolving scientific landscapes. o Mentor and guide peers while independently managing multiple projects, ensuring on-time delivery with clear, effective communication. o Experienced in communicating complex scientific concepts to broad audiences, from public engagement to expert clinicians and scientists - enhancing knowledge dissemination and impact. o Strong interest and engagement in entrepreneurship and business courses (BIST | ESADE), supporting an innovative approach to translational research. DOI: 10.1039/d2cs00197g
o Collaborated closely with clinician Dr. Ramón Salazar (former Director and current Head of Oncology at ICO) to initiate Investigator-Initiated Trials (IITs), fostering translational research that bridges the lab and clinic. o Finalizing key projects in partnership with international collaborators at Peter MacCallum Cancer Centre (Melbourne), ensuring robust cross-institutional progress. o Publishing significant findings in a high-impact, peer-reviewed translational journal (Blood), advancing understanding in cancer biology and therapy development. DOI: 10.1182/blood.2020007452
o Designed and implemented a genetic model to impair ribosome biogenesis in lymphoma cells using an inducible shRNA system, enabling functional studies of cell death and therapeutic sensitivity. Gained hands-on experience in molecular cloning, retroviral transduction, radioisotope-based protein synthesis assays (³H-leucine), and advanced cell culture techniques. o Investigated mechanisms of lymphoma regression through a range of molecular biology techniques, assessing protein and RNA expression (Western blot, qRT-PCR), protein interactions (IP, RNA-IP) and post-translational modifications. o Developed and optimized in vivo protocols for inducing and treating lymphoma in murine models; monitored disease progression and therapeutic response to RNA Pol I inhibitors (Actinomycin D, CX5461) to support translational research and the final aim of supporting a drug repurposing clinical trial in humans. o Designed and performed flow cytometry-based toxicity assessments to evaluate on-target effects and immunological side effects in myeloid and lymphoid populations. o Led in silico drug sensitivity analyses using the GDSC human database (>700 cell lines), identifying predictive biomarkers and strengthening data analytics skills in R programming. o Contributed to peer-reviewed publications in high-impact journals (EMBO Journal), collaborated with international partners, and supported a translational oncology project funded by AECC (GCB14-2035), targeting resistant colorectal cancer. o Awarded a nationally competitive FPI Fellowship (BES-2015-075840) by the Spanish Ministry of Economy and Competitiveness. o Regular participant in scientific meetings and seminars (RTICC, University of Salamanca, etc.) o Licensed operator of radioactive facilities handling non-encapsulated isotopes (HCUR-FNE-O/89_16, ACPRO, Barcelona). DOI 10.15252/embj.2019103838
4-month international research stay as part of my PhD, hosted by Dr. Ricky Pearson's lab (Cell Signaling Group). o Acquired hands-on experience in in vivo procedures using the Eμ-Myc mouse model, a preclinical system for studying MYC-driven lymphomas. o Contributed to a collaborative preclinical oncology project, focusing on drug mechanism of action and resistance. o Strengthened skills in translational cancer research and animal experimentation. o Resulted in a peer-reviewed publication in Blood, a high-impact translational journal. DOI: 10.1182/blood.2020007452
Characterization of the molecular mechanisms that regulate the intracellular distribution of soluble signaling proteins in the photoreceptor cells of the retina Procedures/Techniques: - Cloning - Cell transfection - Recombinant protein purification - Pull-down assays - Western Blot - Bovine retinal tissue and bovine Rod Outer Segments isolation Grade: 9.9