Singapore
I am currently working as a research assistant professor in the Singapore Lipidomics Incubator (SLING), Life Sciences Institute, National University of Singapore. Over the last few years, my interest has evolved from medicinal organic synthesis to separation sciences, mass spectrometry, and especially their applications in life sciences. This has led me to develop a strong interest in MS-based lipidomics. My research has more recently focused on the development of lipidomics methods to answer lipid biochemistry problems. This is a rapidly growing field of investigation, and I intend to build on my experience to address some of its pressing issues (improved quantification, chemical diversity, natural variation, implications in health and disease…)
Past and current projects include: - lysophosphatidylcholine natural variation - exploration of lipids chemical space occupied by diverse biological species - paleolipidomics: lipids analysis in ancient samples - phosphatidylethanol: a unique lipid involved in yeast ethanol-resistance - plant triglycerides analysis - lipidomics method development
I joined the NUS in January 2009. My main interest within the group is the development of mass spectrometric and chromatographic methods for the analysis of lipids. Since joining the group, I've been involved in LC-MS/MS, MALDI-MS/MS and GC-MS/MS analysis of diverse lipids, including phospholipids, glycolipids, mycolactones, TAGs, galactolipids from various organisms (mycobacteria, yeast, human, plants).
I joined the Lipidomics Research Group in November 2007. My main interest within the group is the hyphenation of chromatographic techniques with mass spectrometry and its application to lipid analysis in particular but also to biomedical and environmental analysis in general. Since joining the group, I've been involved in LC-MS/MS and SFC-MS/MS analysis of various lipids, including isoprostanes, gangliosides and phospholipids, and their metabolism in relation to diverse pathologies such as Alzheimer's disease, atherosclerosis or neuroblastoma.