London, England, United Kingdom
I am currently completing my PhD at the Institute of Ophthalmology regarding glaucoma. I have recently graduated in Biosciences MRes from UCL with specialised research in imaging a retinal dystrophy model at the protein and RNA level at Institute of Ophthalmology. Previously, I have graduated with a 1st in Biology BSc from Queen Mary, University of London. Previously, I have participated in the Computational Neuroscience (Interactive Track) with Neuromatch Academy (Summer 2022). Also, I have contributed to the CATH group (a protein database) by identifying protein domains and researching the functional and evolutionary importance of over 100 groups of similarly structured domains (Summer 2021).
Studied the difference in protein and RNA expression across the retina in wild type and retinal dystrophy mouse models, under the supervision of Dr Colin Chu and Dr Kenneth Harris. This research combined IBEX (iterative bleaching extends multiplexity) and coppaFISH (combinatorial padlock probe amplification fluorescence in situ hybridisation) for the first time, and enabled spatial biology of the retina.
Studied the expression and distribution of chemosensory proteins in Parasteatoda tepidariorum (the common house spider) under the supervision of Dr Angelika Stollewerk. This research gave greater insight into the molecular mechanisms that regulate chemosensory proteins arrangement and could encourage comparative analysis into the development of sensory processing across Arthropods.
Contributed to the CATH protein structure classification database at Christine Orengo’s Lab, UCL in association with the Institute of Structural and Molecular Biology (ISMB). - Identified and isolated constituent protein domains using visualisation software (PyMol and RasMol) - Collated similarly structured domains into over 100 different protein superfamilies - Established superfamilies were used to predict the function of newly discovered proteins and identify evolutionary relationships