Zürich Metropolitan Area
Experienced scientific communication specialist with a PhD in Immunology and over 4 years of expertise in translating complex data into impactful publications and presentations. Proven track record in leading publication planning, regulatory compliance, and stakeholder engagement in rare and complex drug hypersensitivities. Skilled in aligning scientific communication strategies with medical narratives and evidence generation. Committed to mentoring interns and junior scientists and fostering professional growth.
- Oversee routine diagnostics for the cytokine release lymphocyte transformation test (Cyto-LTT). - Ensure Quality Control of laboratory results. - Lead author of drug immunogenicity reports for pharmaceutical clients. - Present research and diagnostic updates on "Drug Hypersensitivity" at conferences / webinars for pharmaceutical professionals (European Immunogenicity Platform / International Society of Pharmacovigilance). - Data visualisation and publication writing lead.
- Lead author of drug immunogenicity reports for pharmaceutical clients. - Present research and diagnostic updates on "Drug Hypersensitivity" at conferences / webinars for pharmaceutical professionals (European Immunogenicity Platform / International Society of Pharmacovigilance). - Data visualisation and publication writing lead.
- Implementation of research & development strategies for cellular immunology diagnostics. - Immunology consultation support for adverse drug reactions. - Conceptualisation & writing of research publications. - Represent ADR-AC in scientific conferences. - Communicate scientific interests and news from ADR-AC with various stakeholders (media / business development / healthcare professionals / international outreach). - Yearly mentoring of biomedical laboratory interns (medi - Zentrum für medizinische Bildung).
- Social Media (LinkedIn) communications. - Documentation Writer: creating templates for sponsoring contracts, invoices & award certificates. - Funding & sponsoring applications. - Organising Committee for 1st Annual Symposium (2022).
I'm passionate in helping others achieve mindful balance in their lives through movement. Combining my hobby in Yoga with community outreach such as donations-based public classes enables me to raise awareness and funds for charitable causes I empathise with, such as environmental preservation. I regularly teach both private classes and group classes in Yoga studios.
Gained as a PhD student in the Institute of Pathology, University of Bern. Project: "mRNA Splicing and Epithelial Integrity". Supervisor: Philippe Krebs, PhD. Funding: Swiss National Science Foundation; Gertrud-Hagmann-Stiftung für Malignom-Forschung. In this project, I am interested in studying the effects of dysregulated mRNA splicing in intestinal epithelial cells and how this (a) impacts the integrity of the intestinal epithelial barrier, (b) if this subsequently alters the adjacent microbiota and the mucosal immune system, and (c) if this promotes intestinal immunopathology. This project will involve using in vivo mouse models, in vitro cell cultures and intestinal organoids, and translational work with Inflammatory Bowel Disease (IBD) and colorectal cancer patients' samples. Research students mentored: 1) Patrick van Delden (2019), 7-months internship for MSc thesis. Project: The role of ESRP1 in Epithelial-to-Mesenchymal transition. 2) Benjamin Andreas Grädel (2018), 10-weeks internship for BSc thesis. Project: Modulation of intestinal immunopathologies by epithelial cell alternative mRNA splicing. 3) Pascal Martin Guntern (2017), 10-weeks internship for BSc thesis. Project: Elucidating pathologic mechanisms caused by aberrant splicing in intestinal epithelial cells. --- Related publications: 1) Thoo L, Noti M & Krebs P. (2019). Keep calm: The intestinal barrier at the interface of peace and war. Cell Death & Disease 10:849. 2) Mager LF, Koelzer V, Stuber R, Thoo L et al. (2017). The ESRP1-GPR137 axis contributes to intestinal pathogenesis. eLife 6:e28366.
Project: “Fluorescence characterisation and in vitro toxicity evaluation of carbon nanoparticles (CDots)”. Supervisor: Adi Idris, PhD. Treated J774.1 mouse macrophage cell line with CDots. Analysed for toxicity of CDots on cells using MTT Assay. Also detected for fluorescence of CDots within cells using both microscopy & flow cytometry. I joined this lab group after my MSc studies to both involve myself in on-going research in my home country, and to continue my scientific training in the interim before starting my PhD studies. This work was to provide preliminary data for further research in utilising CDots for drug delivery. --- Related publication: Thoo L, Fahmi MZ, Zulkipli IN, Keasberry N & Idris A. (2017). Interaction and cellular uptake of surface-modified carbon dot nanoparticles by J774.1 macrophages. Central European Journal of Immunology 42(3): 324-330.