Villaz-Saint-Pierre, Fribourg, Switzerland
Development of bottom-up deep learning models. Network of neural networks (autoencoders, classification...) whose structure develop according to the rules of Self-Organizing Map could be a robust alternative to top-down machine learning
PhD in Laboratory of neurotherapy and neuromodulation Thesis title: Genome editing (using CRISPR/Cas9 system) for Huntington’s disease Plasmid and viral vector production, Molecular Biology, WB, RTqPCR, Surveyor (indels detection assay). NGS, iPSCs culture, in vivo stereotaxic viral vectors injections, immunohistochemistry (IHC), Epifluorescence and confocal microscopy, Bioinformatics analysis, Statistical analysis
Master internhip in Laboratory of Neurotherapies and Neuromodulation Master project: Genome editing (using CRISPR/Cas9 system) for Huntington’s disease Plasmid production, WB, Surveyor (indels detection assay), Mouse primary cell cultures, in vivo stereotaxic viral vectors injections, immunohistochemistry (IHC), Epifluorescence microscopy
Emploi étudiant
Trainee in Psychiatric Neuroscience center (CNP) Involvement of CRTC1 gene in stress induced mouse depression phenotype RTqPCR, Western Blot, Forced swim test, genotyping